HERBAL
& SPICE EXTRACT
Technology/Process Description:
Arjuna Natural Extracts Ltd is a global manufacturer and exporter
of Standardized Herbal and Spice Extracts, specialized Essential Oils and Omega
3 fatty acids from marine and vegetable source, in Oil, Powder and Emulsion
forms. Arjuna has world-class R&D facility for in house research
with high- end machinery.
Arjuna’s manufacturing facility makes use of the most
technologically advanced equipments to assure consistent product quality and
efficient streamlined service. It follows strict GMPs to guarantee standardized
extract quality, purity and potency. The facility has the capacity to handle
product volumes ranging from a few 100 kilograms to several 100 metric tones.
Arjuna owns most modern state of the art laboratory approved by
the Ministry of Science and Technology , Govt. of India, with the latest
facilities like HPTLC (Nassaga), HPLC, UV, RI, densitometer , spectrometer, gas
chromatograph, etc. which form part of
the R&D for efficient and effective quality control, product improvisation
and innovations.
Technology/Product Specifications:
Product 1: AMLAMAX- INDIAN
gOOSEBERRY EXTRACT
The extraction process is a
multi-stage phenomenon which involves pulverizing, extraction and evaporation. The same process is used for extraction of different kinds
of herbs. First the cleaned raw material (herb) is taken .Raw material goes
through pulverizer which crushes to give powdered form of the raw material.
Solution of that powder is made using solvent which is herb specific. The
process of preparation of AMLAMAX is as follows:
AMLAMAX Extract Making Process
Indian
Gooseberry
The two main variants are AMLAMAXTM (AET-301) and
AMLAMAXTM (AET-205). The benefits and applications
The properties of these two products
are as follows.
|
AMLAMAX™ |
|
|
|
Product
code |
AED-205 |
AET
– 301 |
|
Colour
and appearance |
Cream
to pale yellow powder (Hygroscopic) |
Pale yellowish
brown to off-white granulated powder(Hygroscopic) |
|
Active
ingredients |
Polyphenols,
natural vitamins and minerals |
Natural
Vitamins, minerals and polyphenols |
|
Polyphenol
content |
35 – 45%
(Titration method) |
Not
less than 30% (Titration method) |
|
Emblicanin
A content (Hydrolysable gallo ellagic tannins) |
Minimum
20% (HPTLC method) |
Minimum
10% (HPTLC method) |
|
Recommended
Dosage |
500-1000
mg per day |
1000-2000
mg per day |
|
Applications |
Beverage,
Brisk Effervescent Tablets |
Tablets,
Capsules |
Product 2:
BIOCURCUMAX-TURMERIC EXTRACT
Biocurcumax™
offers a unique technique and concept to significantly enhance the
bio-availability and thus the bio-activity retained for a longer period at an
appreciably higher level as compared to conventional curcumin for enhanced
efficacy, safety and usage convenience. The extract making process is as
follows:
Extract
Making Process
Product
Name |
Biocurcumax
(Turmeric Extract) |
|
The Raw
Material |
Turmeric |
|
Scientific
Name |
Curcuma
longa |
|
Colour and
appearance |
Orange red
powder |
|
Odour |
Characteristic |
|
Curcumin
Content |
80.60% |
|
Product
Code |
|
Research at Arjuna revealed that the bioavailability of curcumin could be
enhanced about 10-fold by blending curcumin with turmerone, the major
constituent of the essential oil from turmeric (Patent pending). Turmerone
itself has anticancer and antiinflammatory properties and a synergistic
enhancement of the bioactivity of curcumin could be expected from the product.
Curcumin (1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione)is
the active ingredient isolated from Turmeric, that imparts Golden yellow
pigmentation to the material.
1. Curcumin as an Antioxident
The Biocurcumax Turmeric Extract
ensures:
·
Unmatched
bioavailability and enhanced bioactivity
·
Application
and Dosage flexibility
·
Availability
in granule and powder forms
·
For
Pharma, nutraceuticals, functional foods/drinks, capsules, tablets and
functionalizers.
Product 3: AKBAMAX-BOSWELLIA SERRATA EXTRACT
Boswellia
serrata has been traditionally used in India and other countries since ancient times
for the treatment of several diseases including inflammatory disorders and
cancer with minimum side effects. The active constituents of the extract,
namely, boswellic acids were shown to inhibit 5-lipoxygenase and human
leukocyte elastase and were shown to be direct, non-redox inhibitors of
mammalian 5-lipoxygenase. In experimental animal models, boswellic acids have
been shown to be beneficial in Crohn's disease, ulcerative colitis and ileitis.
Boswellia extract also showed inhibitory action on topoisomerase I and II, in
vitro. The extract also induced caspase activation-dependent apoptosis in
various cancer cell lines. AKBAmax™ was ~3 times more effective than
camptothecin, a drug normally prescribed in colorectal cancer cases that are
refractory to standard chemotherapy treatment. Boswellic acids were reported to
increase intracellular calcium and activity of mitogen activated protein kinase
(MAPK) in human isolated leukocytes.
Boswellic acids
are a mixture of 6 components of which AKBAmax™ (3-O-acetyl-11-keto- boswellic
acid) is a minor component, constituting only 2-3% of the total boswellic
acids. However, AKBAmax™ has the highest pharmacological effect among the
various boswellic acids.
|
Product
code |
AKBAmax™–
010 |
|
Product
name |
Boswellia
serrata Extract |
|
Physical
state |
Free
flowing powder |
|
Colour |
Off
white to pale yellow |
|
Odour
and taste |
Characteristic,
resinous |
|
Active
ingredient |
Boswellic
acids- 70% |
|
AKBAmax™ |
10%
Minimum |
Arjuna
has succeeded in concentrating the AKBAmax™ by chromatographic enrichment up to
70%, thus enhancing the biological effects of boswellia, simultaneously
reducing the dosage required, as compared to commercial boswellia extracts.
|
COMPARISON CHART |
||
|
Particulars |
Conventional Boswellia Extract |
AKBAmax™ 010 |
|
Colour
and appearance |
Off
white to pale yellow free flowing powder with a characteristic resinous taste |
Off
white to pale yellow free flowing powder with a characteristic resinous taste |
|
Boswellic
acid(Titration method) |
70% |
70% |
|
Boswellic
acid(HPLC method) |
35
– 45% |
35
- 45% |
|
AKBAmax™
(HPLC method) |
2
– 3% |
10
- 15% |
|
Total
acetyl boswellic acid |
15
– 20% |
35
- 45% |
|
Solubility |
Soluble
in alcohol |
Soluble
in alcohol |
|
Bulk
density (gm/ml) (Tapped) |
0.25
– 0.65 |
0.4
- 0.8 |
|
Bulk
density (gm/ml) (Untapped) |
0.15
– 0.55 |
0.2
- 0.5 |
|
Recommended
dosage |
1000
mg - 1500 mg/day |
250
mg - 500 mg/day |
Company Profile
|
Company Name |
Arjuna Natural Extracts Ltd. |
|
Address |
Bank Road, Aluva
683101,Kerala,India |
|
Contact person |
Mr. P.J Kunjachan |
|
Phone |
+91-484-2622644 |
|
Fax |
+91-484-2532404 |
|
E-mail |
|
|
Web Site |
|
|
Year of Establishment |
1992 |
|
Product(s) Manufactured |
Herbal and Spice Extracts, Marine
Extracts |
|
Production (FY-05) (Products
contributing most to the sales) |
Herbal, Spice Extracts – 115 M Ton,
Marine Extracts 58 M Ton |
|
Sales Turnover |
FY 05: USD 3.0 Mn FY 04: USD 2.2 Mn FY 03: USD 3.6 Mn |
|
Conformity to Standards |
Indian Standards |
|
Compliance to ISO |
ISO 9001-2000 |
|
Foreign Collaboration |
Nil |
|
Manpower Total (Nos.) |
S&T 40 ,Others 60 |
|
Raw Materials / Equipment used |
Gooseberry for Gooseberry Extract |
|
Effluent Generated |
Non Polluting |
Broad Profile of Project Offer
|
Project |
To Manufacture Herbal and Spice
Extract |
|
Capacity per Annum |
320 M.T. |
|
Land Requirements |
20000 Sq.M |
|
Building Requirements |
800 Sq.M |
|
Plant & Machinery and Test
Equipment |
Pulverizer, Evaporator, Extractor, High Performance Thin
Layer Chromatograph (HPTLC), HPLC and UV Spectrophotometer |
|
Electrical Installation |
60 |
|
Implementation Period |
8 Months |
|
Manpower Required |
10 |
|
Raw Materials / Equipment Required |
Gooseberry, Turmeric |
|
Total Project Cost |
USD 4 Mn (Approx.) |
|
Expected Annual Sales |
USD 2.8 Mn |
|
Profitability |
14% |
|
Form of Offer |
Turnkey Project |